Valyu
Biotech & Pharma

Evidence your R&D agents can cite, from target to label.

Full-text papers, clinical trials, chemistry, structures and patents in one API, for teams building AI across discovery and development.

ONE PROGRAMME, FIVE STAGESTargetOpen TargetsPreclinicalChEMBLClinicalTrialsRegulatoryDailyMedPost-marketPubMedEach stage draws on different sources

Pipeline

Across the pipeline.

Each stage asks different questions of different sources. Pick a stage.

Questions teams ask at this stage

  • What human genetic evidence links TYK2 to autoimmune disease?
  • Which cell types express the target, and what happens on knockout?
  • Is there a tractable binding site, and what chemical matter already exists?
  • Who else is in the clinic on this target, and at what phase?
For
Discovery biologyComputational biologyTarget assessment
Sources it reads
PubMed full textOpen TargetsNCBI GeneClinVarChEMBLClinicalTrials.gov
Explore target discovery →

PCSK9

One target, followed through the pipeline.

PCSK9, from a genetic observation to an approved class, as a Valyu search would find it.

Target
Do people with less PCSK9 have fewer heart attacks?

Loss-of-function carriers had lower LDL and markedly lower coronary risk.

Cohen et al., NEJM, 2006
Preclinical
Does blocking PCSK9 lower cholesterol in animals?

A neutralising antibody reduced serum cholesterol in mice and non-human primates.

Chan et al., PNAS, 2009
Clinical
Does lower LDL from PCSK9 inhibition reduce events?

Evolocumab reduced major cardiovascular events on top of statins.

Sabatine et al., NEJM, 2017
Regulatory
What was it approved for, and when?

Approved in the US in 2015 for LDL lowering; cardiovascular risk reduction added in 2017.

FDA label
Post-market
What came next in the class?

An siRNA, inclisiran, halved LDL with twice-yearly dosing.

Ray et al., NEJM, 2020

For investors & BD

Diligence the science, not the deck.

Test an asset’s mechanism, trial record and patent position against the full literature before the term sheet.

  • Does the human genetics support the mechanism the company claims?
  • How did every prior trial on this target read out?
  • Who holds the composition-of-matter patents, and when do they expire?
  • Which competitors are ahead, and by how many phases?

Clinical software

Building clinical or health software?

The same trial, label and literature data grounds clinical decision support, prior authorisation and medical information tools. Every conclusion carries a citation a clinician can open.

Clinical decision support · first-line therapy for EGFR exon 19 deletion NSCLCIllustrative
EvidenceFindingSource
RecommendationOsimertinibFLAURA, NEJM
LabelApproved first line, exon 19 and 21 mutationsDailyMed
Trial evidenceMedian PFS 18.9 vs 10.2 monthsClinicalTrials.gov

Benchmarks

Proof on medical and biology questions.

MedAgent

482 hard medical questions, including clinical trials and drug labels, curated from 10 medical benchmarks.

Valyu48%
Google45%
Exa44%
Parallel42%

FAQ

Questions from R&D teams.

Can we separate preprints from peer-reviewed papers?
Yes. Preprints from bioRxiv and medRxiv are labelled and can be included or excluded per request.
How current are trial records?
ClinicalTrials.gov and DailyMed drug labels update in real time, so new registrations, results and label changes appear as they post.
Which patent offices do you cover?
USPTO (8M+ filings from the early 2000s) and EPO (4M+ filings back to 1978), with full text and figures, updated weekly.
ENTERPRISE

Enterprise on Valyu.

Private indexes on your firm's internal data, enterprise controls, and engineers who ship with you.

Talk to our team
Security and reliability
Security and reliability

SOC 2, Zero Data Retention, SSO with SAML or OIDC, scoped tenant isolation. US, EU, and UK deployment options, or dedicated in your VPC.

Private Index
Private Index

State-of-the-art retrieval on internal data: lab notebooks, internal reports, trial data, research archives. Agents run on your own research and every Valyu source, in one call.

Forward Deployed Engineers
Forward Deployed Engineers

When the API needs to go further, our engineers ship with you. Custom DeepResearch agents and vertical indexes tuned to your field.

See it on your own programme

Send us a target. We’ll send back the dossier.

Genetics, tractability, clinical precedent and competition, cited line by line, before your first call with us.